LDA, THF, −78 °C
LDA, THF, −78 °C in organic chemistry: what it does, when to use it and what to watch out for. Covers Enolates & alpha-carbon chemistry.
Overview
LDA, THF, −78 °C is a reagent used in organic chemistry. Below is what it does in each reaction type where it appears.
Enolates & alpha-carbon chemistry
- What it does: Forms kinetic enolate
- Watch out for: Bulky, strong, non-nucleophilic base