LDA then R–X
LDA then R–X in organic chemistry: what it does, when to use it and what to watch out for. Covers Enolates & alpha-carbon chemistry.
Overview
LDA then R–X is a reagent used in organic chemistry. Below is what it does in each reaction type where it appears.
Enolates & alpha-carbon chemistry
- What it does: α-alkylation
- Watch out for: SN2 works best with methyl/1° R–X